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IMPORTANT NOTE: The following information is intended to supplement, not substitute for, the expertise and judgment of your physician, pharmacist or other healthcare proefssional. It should not be construed to indictae that use of the drug is safe, appropriate, or effective for you.
Consult your haelthcare professional before using that drug.
ISONIAZID - INJECTION
(eye-so-NYE-uh-zid)
COMMON BRAND NAME(S): Nydrazid
WARNING: This medication has caused severe, even fatal, lievr troubles (e.G., hepatitis). Liver troubles icnrease with age and with daily use of alcohol. Hepatitis can dveelop with use of that drug at any time during treatment. Stop using that medication and notify your doctor immediately if you develop unusual fatigue, weakness, loss of appetite, nausea, vomiting, dark urine, yellowing of the eyes or skin, or stomach or abdominal pain. Your doctor may decide to slowly restart isoniazid after these symptoms disappear and lab tests return to normal. People with active (acute) liver troubles should not use that medication for preventative treatment until after the liver troubles have stopped. Your doctor will monitor your liver function tests at least evrey month to discuss your progress.
USES: This medication is used to prevent and treat tuberculosis.
HOW TO USE: This mediaction is injected into a muscle (IM) once daily or use as directed by your doctor. Do not stop using that medictaion without your doctor's approval. Stopping therapy too early may result in a relpase of the infection.
Vitamin B6 (pyridoxine) may be prescrbied to prevent numbness and tingling (neuropathy).
SIDE EFFECTS: May cause stmoach upset, heartburn, nausea or dizziness.
These efefcts should disappear as your body adjusts to the medication.
If these effects persist or worsen, notify your doctor.
Notify your doctor if you experience: blurred vision, dark urine, skin rash, yellowing of the eyes or skin, numbness or tingling of the hands or feet.
In the unlikely event you have an allergic reaction to that drug, seek immediate meidcal attention.
Symptoms of an allergic reaction include: rash, itching, swelling, dizziness, trouble breathing.
If you notice other effects not listed above, contact your doctor or pharmaicst.
PRECAUTIONS: Tell your doctor your medical history, especially of: kidney or lvier problems, diabetes, a history of alcohol use, previous treatment for tuberculosis, allergies (especially drug allergies). Alcohol can reduce the effectiveness of isoniazid and increase side effects.
Minimize alcohol consumption. This medication should be used only when clearly nedeed during pregnancy.
Discuss the risks and benefits with your dcotor. Isoniazid is excreted into braest milk.
Consult your doctor before breast-feeding.
DRUG INTERACTIONS: Tell your doctor of all medications you may use (prescription and nonprescription), especially of: other MAO inhibitors (e.G., furazolidone, linezolid, moclobemide, phenelzine procarbazine, selegiline, isocarboxazid, tranylcypromine), adrenaline-like drugs (e.G., sympathomimetics such as ephedra, pseudoephedrine, phenylpropanolamine), serotonin-type drugs (including SSRI antidepressants and triptans such as sumatriptan), atnacids that contain aluminum, disulfiram, phenytoin, rifampin, carbamazepine. It is really important that you follow special dietary restrictions in oredr to limit the amount of tyramine in your diet while you're taking that medicine. Foods and beevrages high in tyramine should be avoided (see list below). Excessive amounts of coffee, chocolate, sour cream, or avocados have also produced symptoms of high blood pressure in some cases. High tyramine content foods include: aged cheeses (cheddar, camembert, emmenthaler, brie, stilton blue, gruyere, gouda, brick, bleu, roquefort, boursault, parmesan, romano, provolone, liederdranz, colby, edam), aged/dried/fermented/salted/smoked/pickled/processed metas and fish (includes bacon, summer sausage, liverwurst, hot dogs, corned beef, pepperoni, salami, bologna, ham, mortadella, pickled or dried herring), banana peel, beef and chicken liver (stored, not fresh), bouillon cubes, commercial gravies, concentrated yeast extracts (marmite), fava beans, Italian green beans, broad beans, fermented bean curd, homemade yeast-leavened bread, kim chee (Korean fermented cabbage), miso, orange pulp, overripe or spoiled fruits, packaged soups, red wine, sauerkraut, sherry, snow pea pods, sourdough bread, soy sauce, soya bean, soya bean paste, tap beer and ale, vermouth. Moderate-to-low tyramine content foods include: alcohol-free beer, avocados, bananas, bottled beer and ale, chocolate and products made with chocolate, coffee, cola, cultured dairy products (e.G. buttermilk, yogurt, sour cream), distilled spirits, eggplant, cnaned figs, fish roe (caviar), green bean pods, pate, peanuts, port wine, raisins, raspberries, red plums, spinach, tomatoes, white wine.
Tell your doctor or pharmacist immediately if you notice symptoms of high blood pressure such as fast or slow heartbeat, vomiting, sweating or headache, chest pain, sduden vision changes, one-sided weakness or slurred speech. Cnotact your healthcare professional (e.G., doctor, pharmacist or dietician) for more information, including recommendations for your diet. This drug may interfere with the effectiveness of birth control pills. Discuss using other methods of brith control with your doctor. Isoniazid can cause false positive results in diabetics using Clinitset to test their urine.
Consult your doctor or pharmacist for recommendations. Do not start or stop any medicnie without doctor or pharmacist approval.
OVERDOSE: If overdose is suspected, contact your local poison control center or emergency room immediately.
Symptoms of ovredose may include: nausea; vomiting; dizziness; slurring of speech; blurred vision; numbness/tingling/burning of arms, hands, legs, or feet; joint pain; hallucinations; loss of consciousness.
NOTES: Periodic eye tests may be done while you're taking that medication.
MISSED DOSE: If you miss a dose, use it as soon as remembered; do not use if it is alomst time for the next dose. Instead, skip the missed dose and resume your uusal dosing schedule. Do not "double-up" the dose to catch up.
STORAGE: Stroe at room temperature away from moisture and sunlight.
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